Gene
vav3b
- ID
- ZDB-GENE-070912-251
- Name
- vav 3 guanine nucleotide exchange factor b
- Symbol
- vav3b Nomenclature History
- Previous Names
-
- fk86g11
- si:ch211-255p13.2
- wu:fk86g11
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be involved in intracellular signal transduction. Orthologous to human VAV3 (vav guanine nucleotide exchange factor 3).
- Genome Resources
- Note
-
There are some attribution errors between ntng1b (ZDB-GENE-070912-250) and vav3b (ZDB-GENE-070912-251). ENSDARG00000073713 should only be attributed to ntng1b. ENSDARG00000073713 is mistakingly attributed to both genes. vab3b should only be associated with ENSDARG00000075962. ntng1b should be associated with these transcripts: "vav3b"-201, "vav3b"-202 and "vav3b"-203 vav3b should be associated with these transcripts: vav3b-204, vav3b-205, vav3b-206 and vav3b-207
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR022613 | Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain |
| Domain | IPR035734 | VAV3 protein, second SH3 domain |
| Domain | IPR037832 | Vav, PH domain |
| Family | IPR003096 | Smooth muscle protein/calponin |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Length | Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain | Calponin homology domain | CH domain superfamily | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SH2 domain | SH2 domain superfamily | SH3 domain | SH3-like domain superfamily | Smooth muscle protein/calponin | VAV3 protein, second SH3 domain | Vav, PH domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:X1WEX4
|
822 | ||||||||||||||||
|
UniProtKB:A0A8M2BAQ7
|
853 | ||||||||||||||||
|
UniProtKB:B0S6C8
|
826 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance