Gene

adamts9

ID
ZDB-GENE-070814-6
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 9
Symbol
adamts9 Nomenclature History
Previous Names
  • loc (1)
  • pimienta locura (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable metalloendopeptidase activity. Acts upstream of or within endocrine pancreas development and pancreas regeneration. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including digestive system; gonad; immune system; lepidotrichium; and nervous system. Used to study scoliosis. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts9 Human Ortholog
No data available
Associated With adamts9 Via Experimental Models
Human Disease Fish Conditions Citations
scoliosis adamts9stl316/stl316 standard conditions Gray et al., 2020
scoliosis adamts9stl756/stl756 standard conditions Gray et al., 2020
scoliosis adamts9stl336/stl336 standard conditions Gray et al., 2020
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR010294 ADAMTS/ADAMTS-like, Spacer 1
Domain IPR041645 ADAMTS, cysteine-rich domain 2
Domain IPR045371 ADAMTS/ADAMTS-like, cysteine-rich domain 3
Family IPR013273 ADAMTS/ADAMTS-like
Family IPR050439 ADAMTS and ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAMTS/ADAMTS-like ADAMTS/ADAMTS-like, cysteine-rich domain 3 ADAMTS/ADAMTS-like, Spacer 1 ADAMTS and ADAMTS-like ADAMTS, cysteine-rich domain 2 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:G3G3K0
InterPro
1643
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA adamts9-201 (1)
Ensembl
Ensembl 10,402 nt
ZFIN BLAST
mRNA adamts9-202 (1)
Ensembl
Ensembl 4,386 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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