ZFIN is now using GRCz12tu for Genomic Data
Gene
adam19b
- ID
- ZDB-GENE-070705-541
- Name
- ADAM metallopeptidase domain 19b
- Symbol
- adam19b Nomenclature History
- Previous Names
-
- si:dkeyp-44a8.1
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Is expressed in nervous system. Orthologous to human ADAM19 (ADAM metallopeptidase domain 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Cox et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cox et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018358 | Disintegrin, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001590 | Peptidase M12B, ADAM/reprolysin |
| Domain | IPR001762 | Disintegrin domain |
| Domain | IPR002870 | Peptidase M12B, propeptide |
| Domain | IPR006586 | ADAM, cysteine-rich domain |
| Domain | IPR034027 | Reprolysin domain, adamalysin-type |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR036436 | Disintegrin domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ADAM, cysteine-rich domain | Disintegrin, conserved site | Disintegrin domain | Disintegrin domain superfamily | EGF-like domain | Metallopeptidase, catalytic domain superfamily | Peptidase M12B, ADAM/reprolysin | Peptidase M12B, propeptide | Reprolysin domain, adamalysin-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q4N9 | InterPro | 923 | |||||||||
| UniProtKB:A0AB32T3D4 | InterPro | 908 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adam19b-201
(1)
|
Ensembl | 4,122 nt | ||
| mRNA |
adam19b-203
(1)
|
Ensembl | 464 nt | ||
| ncRNA |
adam19b-001
(1)
|
Ensembl | 572 nt | ||
| ncRNA |
adam19b-004
(1)
|
Ensembl | 730 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers