Gene
casp3b
- ID
- ZDB-GENE-070607-1
- Name
- caspase 3, apoptosis-related cysteine peptidase b
- Symbol
- casp3b Nomenclature History
- Previous Names
-
- casp3l
- caspase-3b (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be involved in apoptotic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Is expressed in intestinal bulb; muscle cell; and pharyngeal arch. Orthologous to human CASP3 (caspase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
Domain | IPR001309 | Peptidase C14, p20 domain |
Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
Domain | IPR011600 | Peptidase C14, caspase domain |
Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
Protein | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QGI7
|
224 | ||||||
UniProtKB:A0A8M2BKT2
|
285 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
casp3b-201
(1)
|
Havana | 5614 nt |
Interactions and Pathways
No data available
Plasmids
No data available