Gene

adgrb3

ID

ZDB-GENE-070424-99

Name

adhesion G protein-coupled receptor B3

Symbol

adgrb3 Nomenclature History

Previous Names

bai3
zgc:163001

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Is expressed in brain; eye; and testis. Orthologous to human ADGRB3 (adhesion G protein-coupled receptor B3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Harty et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adgrb3 Human Ortholog

No data available

Associated With adgrb3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000203	GPS motif
Conserved_site	IPR017983	GPCR, family 2, secretin-like, conserved site
Domain	IPR001879	GPCR, family 2, extracellular hormone receptor domain
Domain	IPR017981	GPCR, family 2-like, 7TM
Domain	IPR032471	GAIN domain, N-terminal
Domain	IPR043838	Adhesion G protein-coupled receptor B, N-terminal domain
Family	IPR000832	GPCR, family 2, secretin-like
Family	IPR008077	GPCR, family 2, brain-specific angiogenesis inhibitor
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Homologous_superfamily	IPR036445	GPCR family 2, extracellular hormone receptor domain superfamily
Homologous_superfamily	IPR046338	GAIN domain superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat

Domain Details Per Protein

Protein	Length	Adhesion G protein-coupled receptor B, N-terminal domain	GAIN domain, N-terminal	GAIN domain superfamily	GPCR, family 2, brain-specific angiogenesis inhibitor	GPCR, family 2, extracellular hormone receptor domain	GPCR family 2, extracellular hormone receptor domain superfamily	GPCR, family 2-like, 7TM	GPCR, family 2, secretin-like	GPCR, family 2, secretin-like, conserved site	GPS motif	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A0A8M2B381 InterPro	1493
UniProtKB:A0A8M9QG42 InterPro	1437
UniProtKB:A0A8M1RNS0 InterPro	1528
UniProtKB:A0A8M9Q536 InterPro	343

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adgrb3-202 (1) Ensembl	Havana	3647 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	adgrb3-203 (1) Ensembl	Havana	1981 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	adgrb3-204 (1) Ensembl	Havana	789 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	adgrb3-205 (1) Ensembl	Havana	807 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations