ZFIN is now using GRCz12tu for Genomic Data
Gene
slc9a6a
- ID
- ZDB-GENE-070424-104
- Name
- solute carrier family 9 member A6a
- Symbol
- slc9a6a Nomenclature History
- Previous Names
-
- fv47b07
- wu:fv47b07
- zgc:163055
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable sodium:proton antiporter activity. Predicted to be involved in proton transmembrane transport; regulation of pH; and sodium ion transmembrane transport. Predicted to be located in plasma membrane and recycling endosome membrane. Human ortholog(s) of this gene implicated in Christianson syndrome and X-linked female-restricted neurodegenerative disorder with Parkinsonism and cognitive impairment. Orthologous to human SLC9A6 (solute carrier family 9 member A6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Christianson syndrome | Alliance | Intellectual developmental disorder, X-linked syndromic, Christianson type | 300243 |
| X-linked female-restricted neurodegenerative disorder with Parkinsonism and cognitive impairment | Alliance | Neurodegenerative disorder, X-linked, female-restricted, with parkinsonism and cognitive impairment | 301142 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cation/H+ exchanger, CPA1 family | Cation/H+ exchanger, transmembrane domain | Na+/H+ exchanger | Sodium/hydrogen exchanger 6/7/9 |
|---|---|---|---|---|---|---|
| UniProtKB:F1QSJ6 | InterPro | 697 | ||||
| UniProtKB:A0A8M3AP93 | InterPro | 732 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc9a6a-201
(1)
|
Ensembl | 8,162 nt | ||
| ncRNA |
slc9a6a-002
(1)
|
Ensembl | 666 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers