ZFIN is now using GRCz12tu for Genomic Data
Gene
taco1
- ID
- ZDB-GENE-070410-35
- Name
- translational activator of mitochondrially encoded cytochrome c oxidase I
- Symbol
- taco1 Nomenclature History
- Previous Names
-
- zgc:162204
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in regulation of mitochondrial translation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 8. Orthologous to human TACO1 (translational activator of cytochrome c oxidase I).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sun et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 8 | Alliance | Mitochondrial complex IV deficiency, nuclear type 8 | 619052 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR048300 | TACO1/YebC-like, second and third domains |
| Domain | IPR049083 | TACO1/YebC-like, N-terminal domain |
| Family | IPR002876 | Transcriptional regulator TACO1-like |
| Homologous_superfamily | IPR017856 | Integrase-like, N-terminal |
| Homologous_superfamily | IPR026564 | Transcriptional regulator TACO1-like, domain 3 |
| Homologous_superfamily | IPR029072 | YebC-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Integrase-like, N-terminal | TACO1/YebC-like, N-terminal domain | TACO1/YebC-like, second and third domains | Transcriptional regulator TACO1-like | Transcriptional regulator TACO1-like, domain 3 | YebC-like |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QP29 | InterPro | 308 | ||||||
| UniProtKB:A0AB32U353 | InterPro | 255 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers