Gene
pdlim4
- ID
- ZDB-GENE-070308-5
- Name
- PDZ and LIM domain 4
- Symbol
- pdlim4 Nomenclature History
- Previous Names
-
- ril (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization; heart development; and muscle structure development. Predicted to localize to Z disc; actin cytoskeleton; and adherens junction. Human ortholog(s) of this gene implicated in osteoporosis. Is expressed in several structures, including axial vasculature; digestive system; nervous system; segmental plate; and solid lens vesicle. Orthologous to human PDLIM4 (PDZ and LIM domain 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Te Velthuis et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| osteoporosis | Alliance | {Osteoporosis, susceptibility to} | 166710 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PDZ and LIM domain protein 1-4/Zasp-like, middle domain | PDZ domain | PDZ superfamily | Zinc finger, LIM-type |
|---|---|---|---|---|---|
|
UniProtKB:Q0PWB9
|
349 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
pdlim4-201
(1)
|
Havana | 1656 nt | |
| ncRNA |
pdlim4-002
(1)
|
Havana | 790 nt |
Interactions and Pathways
No data available
Plasmids
No data available