Gene
ccr8.1
- ID
- ZDB-GENE-070302-1
- Name
- chemokine (C-C motif) receptor 8.1
- Symbol
- ccr8.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and chemotaxis. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); sarcoidosis (multiple); and uveitis (multiple). Orthologous to several human genes including CCR1 (C-C motif chemokine receptor 1); CCR2 (C-C motif chemokine receptor 2); and CCR5 (C-C motif chemokine receptor 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C-C chemokine receptor type 1-9-like | Chemokine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:H0WFA9
|
395 | ||||
|
UniProtKB:A0A8M9PNM1
|
395 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccr8.1-201
(1)
|
Ensembl | 2,597 nt | ||
| mRNA |
ccr8.1-202
(1)
|
Ensembl | 1,248 nt |
Interactions and Pathways
No data available
Plasmids
No data available