Gene
ptpmt1
- ID
- ZDB-GENE-070112-272
- Name
- protein tyrosine phosphatase mitochondrial 1
- Symbol
- ptpmt1 Nomenclature History
- Previous Names
-
- im:7137979 (1)
- zgc:158719
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to act upstream of or within phospholipid biosynthetic process and protein dephosphorylation. Predicted to be located in cytoplasm and membrane. Orthologous to human PTPMT1 (protein tyrosine phosphatase mitochondrial 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137979 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Nath et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with ataxia and brain abnormalities | 621199 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000340 | Dual specificity phosphatase, catalytic domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR020422 | Dual specificity protein phosphatase domain |
| Family | IPR042165 | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 |
| Family | IPR044596 | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Dual specificity phosphatase, catalytic domain | Dual specificity protein phosphatase domain | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase-like | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BGB2 | InterPro | 119 | |||||||
| UniProtKB:A1L293 | InterPro | 183 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptpmt1-201
(1)
|
Ensembl | 1,118 nt | ||
| mRNA |
ptpmt1-203
(1)
|
Ensembl | 994 nt | ||
| ncRNA |
ptpmt1-003
(1)
|
Ensembl | 783 nt |
Interactions and Pathways
No data available
Plasmids
No data available