Gene
tyw1
- ID
- ZDB-GENE-060929-688
- Name
- tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
- Symbol
- tyw1 Nomenclature History
- Previous Names
-
- im:6898509
- wu:fb74d01
- zgc:153368
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and tRNA-4-demethylwyosine synthase activity. Predicted to be involved in wybutosine biosynthetic process. Predicted to act upstream of or within tRNA processing. Predicted to be located in membrane. Orthologous to human TYW1 (tRNA-yW synthesizing protein 1 homolog) and TYW1B (tRNA-yW synthesizing protein 1 homolog B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6898509 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001094 | Flavodoxin-like |
| Domain | IPR007197 | Radical SAM |
| Domain | IPR008254 | Flavodoxin/nitric oxide synthase |
| Domain | IPR013917 | tRNA wybutosine-synthesis |
| Family | IPR034556 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase |
| Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
| Homologous_superfamily | IPR029039 | Flavoprotein-like superfamily |
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | Flavodoxin-like | Flavodoxin/nitric oxide synthase | Flavoprotein-like superfamily | Radical SAM | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase | tRNA wybutosine-synthesis |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q08C92
|
730 | |||||||
|
UniProtKB:A0A8M6Z1B5
|
753 |
Interactions and Pathways
No data available
Plasmids
No data available