Gene
cyp24a1
- ID
- ZDB-GENE-060825-1
- Name
- cytochrome P450, family 24, subfamily A, polypeptide 1
- Symbol
- cyp24a1 Nomenclature History
- Previous Names
-
- cyp24a1l
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; and vitamin D 25-hydroxylase activity. Predicted to be involved in response to vitamin D and vitamin D catabolic process. Is expressed in liver. Human ortholog(s) of this gene implicated in colorectal adenoma; gastrointestinal system cancer (multiple); hypercalcemia; lung cancer (multiple); and ulcerative colitis. Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hypercalcemia, infantile, 1 | 143880 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450, families 11 and 27 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A3KNB0
|
505 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp24a1-201
(1)
|
Ensembl | 2,118 nt |
Interactions and Pathways
No data available
Plasmids
No data available