Gene

ptpn23b

ID

ZDB-GENE-060503-179

Name

protein tyrosine phosphatase, non-receptor type 23, b

Symbol

ptpn23b Nomenclature History

Previous Names

ptpn23
si:dkeyp-114f9.2

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Orthologous to human PTPN23 (protein tyrosine phosphatase non-receptor type 23).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn23b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity	618890

Associated With ptpn23b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004328	BRO1 domain
Domain	IPR025304	ALIX V-shaped domain
Homologous_superfamily	IPR038499	BRO1 domain superfamily

Domain Details Per Protein

Protein	Length	ALIX V-shaped domain	BRO1 domain	BRO1 domain superfamily
UniProtKB:A0A2R8QCR7 InterPro	1229
UniProtKB:B7ZV28 InterPro	1215

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptpn23b-201 (1) Ensembl	Havana	3947 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations