Gene
slc8a1b
- ID
- ZDB-GENE-060110-3
- Name
- solute carrier family 8 member 1b
- Symbol
- slc8a1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have calcium:sodium antiporter activity. Predicted to be involved in calcium ion transport; cell communication; and transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including blood; eye; liver; neural tube; and pleuroperitoneal region. Orthologous to human SLC8A1 (solute carrier family 8 member A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001623 | DnaJ domain |
Domain | IPR003644 | Na-Ca exchanger/integrin-beta4 |
Domain | IPR004837 | Sodium/calcium exchanger membrane region |
Domain | IPR032452 | Sodium/calcium exchanger domain, C-terminal extension |
Family | IPR004836 | Sodium/calcium exchanger protein |
Family | IPR051171 | Calcium/Cation Antiporter |
Homologous_superfamily | IPR038081 | CalX-like domain superfamily |
Homologous_superfamily | IPR044880 | NCX, central ion-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Calcium/Cation Antiporter | CalX-like domain superfamily | DnaJ domain | Na-Ca exchanger/integrin-beta4 | NCX, central ion-binding domain superfamily | Sodium/calcium exchanger domain, C-terminal extension | Sodium/calcium exchanger membrane region | Sodium/calcium exchanger protein |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:B2CZC2
|
942 | ||||||||
UniProtKB:A0A8M9P932
|
310 | ||||||||
UniProtKB:Q32SG7
|
944 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
slc8a1b-201
(1)
|
Havana | 2835 nt | |
mRNA |
slc8a1b-202
(1)
|
Havana | 4238 nt | |
mRNA |
slc8a1b-203
(1)
|
Ensembl | 2955 nt |
Interactions and Pathways
No data available
Plasmids
No data available