ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
macroh2a2
- ID
- ZDB-GENE-050913-114
- Name
- macroH2A.2 histone
- Symbol
- macroh2a2 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - H2A2 (1)
- h2afy2
- im:6898017
- wu:fa14g05
- zgc:114051
 
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables transcription cis-regulatory region binding activity. Involved in brain development. Predicted to be located in chromosome. Predicted to be part of nucleosome. Predicted to be active in nucleus. Is expressed in brain; central nervous system; retina; and retinal ganglion cell layer. Orthologous to human MACROH2A2 (macroH2A.2 histone).
- Genome Resources
- Note
- None
- Comparative Information
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- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- 
    
        
    
    
        
        - IMAGE:6898017 (8 images)
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
- 1 Figure from Buschbeck et al., 2009
- Cross-Species Comparison
- Alliance
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Type | InterPro ID | Name | 
|---|---|---|
| Domain | IPR002589 | Macro domain | 
| Domain | IPR007125 | Histone H2A/H2B/H3 | 
| Domain | IPR032454 | Histone H2A, C-terminal domain | 
| Domain | IPR035796 | Core histone macro-H2A, macro domain | 
| Family | IPR002119 | Histone H2A | 
| Family | IPR021171 | Core histone macro-H2A | 
| Homologous_superfamily | IPR009072 | Histone-fold | 
| Homologous_superfamily | IPR043472 | Macro domain-like | 
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | Core histone macro-H2A | Core histone macro-H2A, macro domain | Histone-fold | Histone H2A | Histone H2A, C-terminal domain | Histone H2A/H2B/H3 | Macro domain | Macro domain-like | 
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q4V914 | InterPro | 367 | 
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis | 
|---|---|---|---|---|---|
| mRNA | h2afy2-201
                             (1) | Ensembl | 2,001 nt | ||
| mRNA | h2afy2-202
                             (1) | Ensembl | 678 nt | ||
| mRNA | h2afy2-203
                             (1) | Ensembl | 897 nt | ||
| mRNA | h2afy2-204
                             (1) | Ensembl | 883 nt | 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
