Gene

arhgap12a

ID

ZDB-GENE-050809-38

Name

Rho GTPase activating protein 12a

Symbol

arhgap12a Nomenclature History

Previous Names

im:7153489
si:ch211-159p3.3

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in regulation of GTPase activity. Predicted to localize to cytoplasm. Is expressed in ectoderm. Orthologous to human ARHGAP12 (Rho GTPase activating protein 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7153489 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap12a Human Ortholog

No data available

Associated With arhgap12a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001202	WW domain
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR035491	ARHGAP12, SH3 domain
Family	IPR050729	Rho GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036020	WW domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	ARHGAP12, SH3 domain	PH-like domain superfamily	Pleckstrin homology domain	Rho GTPase-activating protein	Rho GTPase-activating protein domain	Rho GTPase activation protein	SH3 domain	SH3-like domain superfamily	WW domain	WW domain superfamily
UniProtKB:A0A8M9QA49 InterPro	853
UniProtKB:A0A8M2BJ65 InterPro	781
UniProtKB:A0A8M9PYG1 InterPro	648
UniProtKB:A0A8M2BIT3 InterPro	825
UniProtKB:A0A8M9QA59 InterPro	809
UniProtKB:A0A8M9QNP2 InterPro	776
UniProtKB:A0A8M2BIQ0 InterPro	803
UniProtKB:A0A8M9QFU9 InterPro	626
UniProtKB:F6P057 InterPro	831

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arhgap12a-201 (1) Ensembl	Ensembl	1,464 nt	Select Tool
mRNA	arhgap12a-202 (1) Ensembl	Ensembl	876 nt	Select Tool
mRNA	arhgap12a-203 (1) Ensembl	Ensembl	3,776 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations