Gene

fign

ID
ZDB-GENE-050522-339
Name
fidgetin
Symbol
fign Nomenclature History
Previous Names
  • zgc:110229
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have microtubule-severing ATPase activity. Predicted to be involved in cytoplasmic microtubule organization and regulation of double-strand break repair via homologous recombination. Predicted to localize to nucleus. Is expressed in central nervous system; lens placode; and somite. Orthologous to human FIGN (fidgetin, microtubule severing factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fign Human Ortholog
No data available
Associated With fign Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR015415 Spastin/Vps4, C-terminal
Domain IPR047828 Fidgetin, ATPase domain
Family IPR050304 Microtubule-severing AAA ATPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ATPase, AAA-type, core Fidgetin, ATPase domain Microtubule-severing AAA ATPase P-loop containing nucleoside triphosphate hydrolase Spastin/Vps4, C-terminal
UniProtKB:Q503S1 736
UniProtKB:B2GQM4 736
UniProtKB:A0A8M9QFE1 747
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fign-201 (1) Ensembl 3,099 nt
mRNA fign-202 (1) Ensembl 2,227 nt
mRNA fign-203 (1) Ensembl 6,315 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations