Gene
tp53rk
- ID
- ZDB-GENE-050522-123
- Name
- TP53 regulating kinase
- Symbol
- tp53rk Nomenclature History
- Previous Names
-
- fd05d02
- wu:fd05d02
- zgc:110000 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to localize to EKC/KEOPS complex and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907866 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Galloway-Mowat syndrome 4 | Alliance | Galloway-Mowat syndrome 4 | 617730 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase Bud32 | Tyrosine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:F1QB90
|
231 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tp53rk-201
(1)
|
Ensembl | 5,295 nt |
Interactions and Pathways
No data available
Plasmids
No data available