Gene
ascc1
- ID
- ZDB-GENE-050417-80
- Name
- activating signal cointegrator 1 complex subunit 1
- Symbol
- ascc1 Nomenclature History
- Previous Names
-
- zgc:112403 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Involved in several processes, including myotome development; neuromuscular junction development; and thigmotaxis. Human ortholog(s) of this gene implicated in Barrett's esophagus. Is expressed in cardiac muscle; head; and trunk. Orthologous to human ASCC1 (activating signal cointegrator 1 complex subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6901357 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Knierim et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Barrett's esophagus | Alliance | Barrett esophagus/esophageal adenocarcinoma | 614266 |
| Spinal muscular atrophy with congenital bone fractures 2 | 616867 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004087 | K Homology domain |
| Domain | IPR004088 | K Homology domain, type 1 |
| Domain | IPR019510 | A-kinase anchor protein 7-like, phosphoesterase domain |
| Domain | IPR047538 | Activating signal cointegrator 1 complex subunit 1, type I KH domain |
| Family | IPR009210 | Activating signal cointegrator 1 complex subunit 1 |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Length | Activating signal cointegrator 1 complex subunit 1 | Activating signal cointegrator 1 complex subunit 1, type I KH domain | A-kinase anchor protein 7-like, phosphoesterase domain | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q566X5
|
353 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available