Gene
zgc:110366
- ID
- ZDB-GENE-050417-302
- Name
- zgc:110366
- Symbol
- zgc:110366 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7152621 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A8DZH9
|
289 | ||||
|
UniProtKB:U3JA33
|
291 | ||||
|
UniProtKB:A0A8M2BAE4
|
175 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
zgc:110366-201
(1)
|
Havana | 1562 nt | |
| mRNA |
zgc:110366-203
(1)
|
Havana | 1066 nt | |
| ncRNA |
zgc:110366-002
(1)
|
Havana | 766 nt |
Interactions and Pathways
No data available
Plasmids
No data available