Gene

dscama

ID

ZDB-GENE-050310-7

Name

Down syndrome cell adhesion molecule a

Symbol

dscama Nomenclature History

Previous Names

dscam
zDscam (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have cell-cell adhesion mediator activity. Involved in cell migration involved in gastrulation. Localizes to integral component of plasma membrane. Is expressed in nervous system. Orthologous to human DSCAM (DS cell adhesion molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Lu et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dscama Human Ortholog

No data available

Associated With dscama Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR013106	Immunoglobulin V-set domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin domain subtype	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Immunoglobulin V-set domain
UniProtKB:A0A8M2B246 InterPro	1515
UniProtKB:A0A8M9QGN7 InterPro	2025
UniProtKB:Q53CM6 InterPro	2024

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dscama-201 (1) Ensembl	Ensembl	7,164 nt	Select Tool ZFIN BLAST
mRNA	dscama-202 (1) Ensembl	Ensembl	6,036 nt	Select Tool
mRNA	dscama-203 (1) Ensembl	Ensembl	6,267 nt	Select Tool ZFIN BLAST
mRNA	dscama-204 (1) Ensembl	Ensembl	6,081 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations