Gene
sod3a
- ID
- ZDB-GENE-050309-208
- Name
- superoxide dismutase 3, extracellular a
- Symbol
- sod3a Nomenclature History
- Previous Names
-
- im:7151832
- zgc:165473
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151832 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
[Superoxide dismutase, elevated extracellular] |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR018152 | Superoxide dismutase, copper/zinc, binding site |
Domain | IPR001424 | Superoxide dismutase, copper/zinc binding domain |
Family | IPR024134 | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone |
Homologous_superfamily | IPR036423 | Superoxide dismutase-like, copper/zinc binding domain superfamily |
Domain Details Per Protein
Protein | Length | Superoxide dismutase, copper/zinc binding domain | Superoxide dismutase, copper/zinc, binding site | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone | Superoxide dismutase-like, copper/zinc binding domain superfamily |
---|---|---|---|---|---|
UniProtKB:A5PLA4
|
213 |
Interactions and Pathways
No data available
Plasmids
No data available