Gene
pthlha
- ID
- ZDB-GENE-050119-9
- Name
- parathyroid hormone-like hormone a
- Symbol
- pthlha Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have hormone activity and peptide hormone receptor binding activity. Involved in bone mineralization; dorsal aorta development; and embryonic cranial skeleton morphogenesis. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in brachydactyly type E2. Is expressed in several structures, including central nervous system; head; hypertrophic chondrocyte; perichondrium; and pleuroperitoneal region. Orthologous to human PTHLH (parathyroid hormone like hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| brachydactyly type E2 | Alliance | Brachydactyly, type E2 | 613382 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Parathyroid hormone/parathyroid hormone-related protein | Parathyroid hormone-related protein |
|---|---|---|---|
|
UniProtKB:Q1L5E8
|
198 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pthlha-201
(1)
|
Ensembl | 1,242 nt | ||
| mRNA |
pthlha-202
(1)
|
Ensembl | 1,672 nt |
Interactions and Pathways
No data available
Plasmids
No data available