Research
General Information
ZIRC
ZFIN: Gene: extl3
ZFIN ID: ZDB-GENE-041124-2

Gene Name:exostoses (multiple)-like 3
Gene Symbol: extl3
Previous Names: im:7141548, boxer, box
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 2 figure(s) from 2 publications
Directly submitted expression data: 1 figure(s) (1 images) from Thisse et al., 2004 [IMAGE:7141548]
Wild Type Stages, Structures: Zygote:1-cell (0.00h-0.75h) to Hatching:Pec-fin (60.00h-72.00h)
  nervous system, pectoral fin musculature, unspecified, whole organism
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   8 genotypes
Allele(s):   te242, tg308c, tm317c, tm4, tm70g ... (all 8)
Phenotype: (current status)
  Data: 16 figures from 4 publications
  Observed in: behavior, fin, gill, mandibular arch skeleton, mouth ... (all 17)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity (more)
Biological Process embryonic pectoral fin morphogenesis (more)
Cellular Component intrinsic to endoplasmic reticulum membrane (more)
All GO Terms (10)

Protein Families, Domains and Sites:
  • InterPro:IPR004263 (1)
  • InterPro:IPR015338 (1)
  • Pfam:PF03016 (1)
  • Pfam:PF09258 (1)

  • SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    extl3 Encodes [EST] IMAGE:7141548 (1)    (order this)
    [cDNA] MGC:194089 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001008402 (1) 3250 bp
    Polypeptide UniProtKB:Q5U7D2 (1) 917 aa
    Sequence Clusters UniGene:79599 (1)
    All Sequence Information (9)

    OTHER  extl3  GENE / MARKER PAGES:

  • Entrez Gene:493783 (1)
  • Ensembl(Zv8):ENSDARG00000026811 (1)

  • MAPPING INFORMATION:
      LG:  20  Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish extl3  20
    Human EXTL3  8 (p21)
  • OMIM:605744
  • Entrez Gene:2137
  • Mouse Extl3  14 (syntenic)
  • MGI:1860765
  • Entrez Gene:54616
  • Orthology Details

    CITATIONS   (21)