ZFIN ID: ZDB-GENE-041111-259

Gene Name:enhancer of zeste homolog 2 (Drosophila)
Gene Symbol: ezh2

Previous Names: eya2, im:7149338, zgc:136376, zgc:152758
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	10 figure(s) from 4 publications
Directly submitted expression data:	6 figure(s) (10 images) from Thisse et al., 2004 [IMAGE:7149338]
Wild Type Stages, Structures:	Cleavage:2-cell (0.75h-1.00h) to Hatching:Long-pec (48.00h-60.00h)
	central nervous system, optic tectum ... (all 7)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Phenotype: (current status)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	chromatin modification (more)
Cellular Component	nucleus
Molecular Function	DNA binding (more)

All GO Terms (8)

Protein Families, Domains and Sites:

InterPro:IPR001005 (1) InterPro:IPR001214 (1) InterPro:IPR021654 (1)

PROSITE:PS50280 (1)

Pfam:PF00856 (1) Pfam:PF11616 (1)

EC:2.1.1.43 (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

ezh2 Contained in	[BAC] DKEY-117J14 (1)    (order this)
ezh2 Encodes	[EST] IMAGE:7149338 (1)    (order this) [cDNA] MGC:136376 (1)    (order this) , MGC:152758 (1)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001077279 (1)	3759 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX005392 (1)	178765 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q08BS4 (1)	760 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:76424 (1)
All Sequence Information (14)

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OTHER  ezh2  GENE / MARKER PAGES:

Entrez Gene:768133 (1)

VEGA:OTTDARG00000021405 (1)

Ensembl(Zv8):ENSDARG00000010571 (1)

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MAPPING INFORMATION:

LG:  24  Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	ezh2	24
Human	EZH2	7 (q35-q36)	OMIM:601573 Entrez Gene:2146
Mouse	Ezh2	6 (19.20 cM)	MGI:107940 Entrez Gene:14056
Orthology Details

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CITATIONS   (16)