Gene

cdc42bpab

ID

ZDB-GENE-080219-17

Name

CDC42 binding protein kinase alpha (DMPK-like) b

Symbol

cdc42bpab Nomenclature History

Previous Names

fb82d10
si:ch211-89p3.3
wu:fb82d10
zgc:174985

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actomyosin structure organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in lamellipodium. Predicted to be active in actomyosin and cytoplasm. Orthologous to human CDC42BPA (CDC42 binding protein kinase alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdc42bpab Human Ortholog

No data available

Associated With cdc42bpab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000095	CRIB domain
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR001180	Citron homology (CNH) domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR014930	Myotonic dystrophy protein kinase, coiled coil
Domain	IPR017892	Protein kinase, C-terminal
Domain	IPR026611	Serine/threonine-protein kinase MRCK alpha, catalytic domain
Domain	IPR031597	KELK-motif containing domain
Family	IPR050839	Rho-associated Serine/Threonine Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	C1-like domain superfamily	Citron homology (CNH) domain	CRIB domain	KELK-motif containing domain	Myotonic dystrophy protein kinase, coiled coil	PH-like domain superfamily	Pleckstrin homology domain	Protein kinase, ATP binding site	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Protein kinase, C-terminal	Protein kinase domain	Protein kinase-like domain superfamily	Rho-associated Serine/Threonine Kinase	Serine/threonine-protein kinase, active site	Serine/threonine-protein kinase MRCK alpha, catalytic domain
UniProtKB:A0A8M9PSV8 InterPro	1787
UniProtKB:A0A8M9PPH2 InterPro	1800
UniProtKB:A0A8M9PPH6 InterPro	1775
UniProtKB:A0A8M9P2P6 InterPro	1799
UniProtKB:A0A8M2B7M9 InterPro	1768
UniProtKB:A0A8M9PBV1 InterPro	1795
UniProtKB:A0A8M2B7P3 InterPro	1793
UniProtKB:A0A8M6YU74 InterPro	1767
UniProtKB:A0A8M6Z3A6 InterPro	1792
UniProtKB:Q5TZ37 InterPro	1716

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cdc42bpab-201 (1) Ensembl	Ensembl	8,191 nt	Select Tool ZFIN BLAST
mRNA	cdc42bpab-202 (1) Ensembl	Ensembl	1,949 nt	Select Tool ZFIN BLAST
ncRNA	cdc42bpab-002 (1) Ensembl	Ensembl	540 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations