Gene

trdn

ID

ZDB-GENE-041014-193

Name

triadin

Symbol

trdn Nomenclature History

Previous Names

si:dkey-72g4.2
zgc:162523

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable signaling receptor binding activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in sarcoplasmic reticulum membrane. Is expressed in adaxial cell; cardiovascular system; musculature system; somite; and yolk syncytial layer. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Orthologous to human TRDN (triadin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6894188 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Vecchi et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trdn Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
catecholaminergic polymorphic ventricular tachycardia 5	Alliance	Cardiac arrhythmia syndrome, with or without skeletal muscle weakness	615441

Associated With trdn Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR010798	Triadin

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A3KNU6	InterPro	226
UniProtKB:Q5XJD2	InterPro	535
UniProtKB:Q32LR2	InterPro	376
UniProtKB:A0A8M6YWT4	InterPro	981
UniProtKB:A0A8M9P313	InterPro	1063
UniProtKB:A0A8M9PCB1	InterPro	1113
UniProtKB:A0A8M9PQ10	InterPro	1122
UniProtKB:A0A8M9PHX9	InterPro	1109
UniProtKB:A0A8M9PQ15	InterPro	1072
UniProtKB:A0A8M9P311	InterPro	1121
UniProtKB:A0A8M9PTE6	InterPro	1105
UniProtKB:A0AB32T7C1	InterPro	1104
UniProtKB:A0AB32T7C6	InterPro	1118
UniProtKB:A0AB32T941	InterPro	994
UniProtKB:A0AB32TA61	InterPro	1085
UniProtKB:A0AB32TCM8	InterPro	1135
UniProtKB:A0AB32TCW0	InterPro	1076
UniProtKB:A0AB32TE64	InterPro	1122
UniProtKB:A0AB32TED6	InterPro	1122
UniProtKB:A0AB32TEH1	InterPro	1134
UniProtKB:A0AB32TFW4	InterPro	1126

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trdn-201 (1) Ensembl	Ensembl	2,641 nt	Select Tool ZFIN BLAST
mRNA	trdn-202 (1) Ensembl	Ensembl	803 nt	Select Tool ZFIN BLAST
mRNA	trdn-203 (1) Ensembl	Ensembl	1,872 nt	Select Tool ZFIN BLAST
mRNA	trdn-204 (1) Ensembl	Ensembl	771 nt	Select Tool ZFIN BLAST
ncRNA	trdn-004 (1) Ensembl	Ensembl	625 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations