Gene
txnl4a
- ID
- ZDB-GENE-041010-25
- Name
- thioredoxin-like 4A
- Symbol
- txnl4a Nomenclature History
- Previous Names
-
- zgc:103632
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U5 snRNP; and spliceosomal complex. Is expressed in liver. Human ortholog(s) of this gene implicated in Burn-McKeown syndrome. Orthologous to human TXNL4A (thioredoxin like 4A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sorrells et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Burn-McKeown syndrome | Alliance | Burn-McKeown syndrome | 608572 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Dim1 family | Thioredoxin-like superfamily |
|---|---|---|---|---|
| UniProtKB:Q5XJ58 | InterPro | 142 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
txnl4a-201
(1)
|
Ensembl | 875 nt | ||
| mRNA |
txnl4a-202
(1)
|
Ensembl | 895 nt |
Interactions and Pathways
No data available
Plasmids
No data available