Gene

glrx3

ID
ZDB-GENE-041010-22
Name
glutaredoxin 3
Symbol
glrx3 Nomenclature History
Previous Names
  • Grx3 (1)
  • txnl2 (1)
  • wu:fb38e09
  • zgc:103648
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have several functions, including electron transfer activity; iron-sulfur cluster binding activity; and protein disulfide oxidoreductase activity. Involved in hemoglobin metabolic process and iron ion homeostasis. Predicted to localize to cytosol and nucleus. Is expressed in brain; eye; heart; and intermediate cell mass of mesoderm. Orthologous to human GLRX3 (glutaredoxin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Haunhorst et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With glrx3 Human Ortholog
No data available
Associated With glrx3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002109 Glutaredoxin
Domain IPR013766 Thioredoxin domain
Domain IPR033658 Glutaredoxin, PICOT-like
Family IPR004480 Monothiol glutaredoxin-related
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Glutaredoxin Glutaredoxin, PICOT-like Monothiol glutaredoxin-related Thioredoxin domain Thioredoxin-like superfamily
UniProtKB:Q5XJ54 326
UniProtKB:B2GNX4 326
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
AB2-glrx3 monoclonal IgG1 Mouse
1
AB1-glrx3 monoclonal IgG1 Mouse
1
AB4-glrx3 monoclonal IgG1 Mouse
1
AB3-glrx3 monoclonal IgG2a Mouse
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations