Gene
cited2
- ID
- ZDB-GENE-041010-141
- Name
- Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
- Symbol
- cited2 Nomenclature History
- Previous Names
-
- zgc:103418
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have transcription coactivator activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in atrial heart septal defect 8 and ventricular septal defect. Is expressed in several structures, including brain; immature eye; lens; optic primordium; and pharyngeal arch. Orthologous to human CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103418 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Santos et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
atrial heart septal defect 8 | Alliance | Atrial septal defect 8 | 614433 |
ventricular septal defect | Alliance | Ventricular septal defect 2 | 614431 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
congenital heart disease | AB + MO1-cited2 + MO2-cited2 | standard conditions | Santos et al., 2019 |
congenital heart disease | AB + MO2-cited2 | standard conditions | Santos et al., 2019 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR007576 | CITED |
Domain Details Per Protein
Protein | Length | CITED |
---|---|---|
UniProtKB:Q5XJD6
|
222 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
cited2-201
(1)
|
Havana | 2345 nt |
Interactions and Pathways
No data available
Plasmids