Gene

gtf3c4

ID

ZDB-GENE-041008-147

Name

general transcription factor IIIC, polypeptide 4

Symbol

gtf3c4 Nomenclature History

Previous Names

im:7138272
si:dkeyp-10e10.3 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable histone acetyltransferase activity. Predicted to act upstream of or within transcription initiation at RNA polymerase III promoter. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C4 (general transcription factor IIIC subunit 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7138272 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtf3c4 Human Ortholog

No data available

Associated With gtf3c4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR024761	Transcription factor IIIC, 90kDa subunit, N-terminal
Domain	IPR024764	Transcription factor IIIC, putative zinc-finger
Domain	IPR045803	Domain of unknown function DUF5921
Family	IPR044230	General transcription factor 3C polypeptide 4
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Domain of unknown function DUF5921	General transcription factor 3C polypeptide 4	Transcription factor IIIC, 90kDa subunit, N-terminal	Transcription factor IIIC, putative zinc-finger	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A2R8RJ69	InterPro	770
UniProtKB:A0A8N7TDX7	InterPro	770

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	gtf3c4-201 (1) Ensembl	Ensembl		2,545 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations