Gene
drc1
- ID
- ZDB-GENE-041001-218
- Name
- dynein regulatory complex subunit 1 homolog (Chlamydomonas)
- Symbol
- drc1 Nomenclature History
- Previous Names
-
- ccdc164
- sb:eu1661
- si:dkey-65b13.6
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in axonemal dynein complex assembly; cilium-dependent cell motility; and regulation of cilium movement. Predicted to localize to axoneme. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21. Is expressed in Kupffer's vesicle; axis; basal plate midbrain region; nervous system; and pronephric duct. Orthologous to human DRC1 (dynein regulatory complex subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1661 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
primary ciliary dyskinesia 21 | Alliance | Ciliary dyskinesia, primary, 21 | 615294 |
spermatogenic failure 80 | Alliance | Spermatogenic failure 80 | 620222 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Dynein regulatory complex protein | Dynein regulatory complex protein 1/2, N-terminal | Dynein regulatory complex protein 1, C-terminal |
---|---|---|---|---|
UniProtKB:A0A8M9PP45
|
582 | |||
UniProtKB:F1QRC1
|
670 |
Interactions and Pathways
No data available
Plasmids
No data available