wdr18

ID

ZDB-GENE-040905-4

Name

WD repeat domain 18

Symbol

wdr18 Nomenclature History

Previous Names

wu:fa16f06
wu:fb79d07
zgc:92370

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Involved in Kupffer's vesicle development and determination of left/right symmetry. Predicted to be located in dynein axonemal particle. Predicted to be part of nuclear pre-replicative complex and rixosome complex. Is expressed in Kupffer's vesicle; forerunner cell group; liver; and pancreas. Orthologous to human WDR18 (WD repeat domain 18).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92370 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Gao et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdr18 Human Ortholog

No data available

Associated With wdr18 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR026987	WD repeat-containing protein 18, C-terminal domain
Family	IPR045227	WD repeat-containing protein WDR18/Ipi3/RID3
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat