ZFIN is now using GRCz12tu for Genomic Data
Gene
srp68
- ID
- ZDB-GENE-040831-3
- Name
- signal recognition particle 68
- Symbol
- srp68 Nomenclature History
- Previous Names
-
- zgc:92573
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable signal recognition particle binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human SRP68 (signal recognition particle 68).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7160947 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Neutropenia, severe congenital, 10, autosomal recessive | 620534 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Signal recognition particle subunit SRP68 | Signal recognition particle subunit SRP68, RNA-binding domain | SRP68, N-terminal domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:A7YYE9 | InterPro | 593 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers