Gene
ufd1l
- ID
- ZDB-GENE-040718-150
- Name
- ubiquitin recognition factor in ER associated degradation 1
- Symbol
- ufd1l Nomenclature History
- Previous Names
-
- fc55f04
- wu:fc55f04
- zgc:92341
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable polyubiquitin modification-dependent protein binding activity. Acts upstream of or within cellular response to xenobiotic stimulus and enteric nervous system development. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Human ortholog(s) of this gene implicated in DiGeorge syndrome and schizophrenia. Orthologous to human UFD1 (ubiquitin recognition factor in ER associated degradation 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Huiting et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR055417 | Ubiquitin fusion degradation protein UFD1, N-terminal subdomain 1 |
| Domain | IPR055418 | Ubiquitin fusion degradation protein UFD1, N-terminal subdomain 2 |
| Family | IPR004854 | Ubiquitin fusion degradation protein Ufd1-like |
| Homologous_superfamily | IPR042299 | Ufd1-like, Nn domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ubiquitin fusion degradation protein Ufd1-like | Ubiquitin fusion degradation protein UFD1, N-terminal subdomain 1 | Ubiquitin fusion degradation protein UFD1, N-terminal subdomain 2 | Ufd1-like, Nn domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DRD5 | InterPro | 308 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available