Gene
litaf
- ID
- ZDB-GENE-040704-23
- Name
- lipopolysaccharide-induced TNF factor
- Symbol
- litaf Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasmic side of early endosome membrane and cytoplasmic side of plasma membrane. Predicted to be active in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. Is expressed in pronephric duct and pronephric duct opening. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to human LITAF (lipopolysaccharide induced TNF factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91882 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 1C | Alliance | Charcot-Marie-Tooth disease, type 1C | 601098 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LITAF domain containing protein | LPS-induced tumour necrosis factor alpha factor |
|---|---|---|---|
|
UniProtKB:A0A8M3AR44
|
162 | ||
|
UniProtKB:Q6GMG8
|
163 |
Interactions and Pathways
No data available
Plasmids
No data available