Gene
dram2b
- ID
- ZDB-GENE-040625-141
- Name
- DNA-damage regulated autophagy modulator 2b
- Symbol
- dram2b Nomenclature History
- Previous Names
-
- dram2
- fj35e01
- wu:fj35e01
- zgc:86754
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to be involved in photoreceptor cell maintenance and regulation of autophagy. Predicted to be located in endomembrane system and membrane. Predicted to be active in lysosome. Human ortholog(s) of this gene implicated in cone-rod dystrophy 21. Orthologous to human DRAM2 (DNA damage regulated autophagy modulator 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6892548 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 21 | Alliance | Cone-rod dystrophy 21 | 616502 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | DRAM/TMEM150 Autophagy Modulator | Frag1/DRAM/Sfk1 |
|---|---|---|---|---|
| UniProtKB:Q6IQI0 | InterPro | 272 | ||
| UniProtKB:F1R7U0 | InterPro | 273 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dram2b-201
(1)
|
Ensembl | 1,954 nt |
Interactions and Pathways
No data available
Plasmids
No data available