ZFIN is now using GRCz12tu for Genomic Data
Gene
esrrgb
- ID
- ZDB-GENE-040616-4
- Name
- estrogen-related receptor gamma b
- Symbol
- esrrgb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including nuclear steroid receptor activity; steroid binding activity; and zinc ion binding activity. Acts upstream of or within otic vesicle development and otolith formation. Predicted to be located in nucleus. Orthologous to human ESRRG (estrogen related receptor gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- ay556399 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tohmé et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital nonprogressive movement disorder with ataxia and eye movement abnormalities | Alliance | Movement disorder, congenital nonprogressive, with ataxia and eye movement abnormalities | 621639 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR024178 | Estrogen receptor/oestrogen-related receptor |
| Family | IPR027289 | Oestrogen-related receptor |
| Family | IPR050200 | Nuclear hormone receptor family NR3 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Estrogen receptor/oestrogen-related receptor | Nuclear hormone receptor | Nuclear hormone receptor family NR3 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Oestrogen-related receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5RJ38 | InterPro | 444 | ||||||||
| UniProtKB:B3DIZ0 | InterPro | 420 | ||||||||
| UniProtKB:A0AC58I2I3 | InterPro | 444 | ||||||||
| UniProtKB:A0AC58I2I4 | InterPro | 444 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
esrrgb-201
(1)
|
Ensembl | 1,825 nt | ||
| mRNA |
esrrgb-202
(1)
|
Ensembl | 1,372 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers