Gene
arhgef18a
- ID
- ZDB-GENE-040516-14
- Name
- rho/rac guanine nucleotide exchange factor (GEF) 18a
- Symbol
- arhgef18a Nomenclature History
- Previous Names
-
- arhgef18
- wu:fc21e04
- wu:fj05f11
- zgc:85686
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human ARHGEF18 (Rho/Rac guanine nucleotide exchange factor 18).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Retinitis pigmentosa 78 | 617433 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | ARHGEF1-like, PH domain | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | PH-like domain superfamily | Pleckstrin homology domain |
---|---|---|---|---|---|---|
UniProtKB:Q6NSP2
|
940 | |||||
UniProtKB:A0A8M3AXD6
|
940 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
arhgef18a-201
(1)
|
Havana | 4184 nt | |
mRNA |
arhgef18a-202
(1)
|
Havana | 389 nt | |
mRNA |
arhgef18a-203
(1)
|
Havana | 554 nt |
Interactions and Pathways
No data available
Plasmids
No data available