Gene

pacsin3

ID

ZDB-GENE-040426-984

Name

protein kinase C and casein kinase substrate in neurons 3

Symbol

pacsin3 Nomenclature History

Previous Names

fa11d03
fj67e09
wu:fa11d03 (1)
wu:fj67e09 (1)
wu:fq16a06 (1)
zgc:56324

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have cytoskeletal protein binding activity and phospholipid binding activity. Involved in notochord cell differentiation and notochord formation. Localizes to plasma membrane. Is expressed in several structures, including endoderm; epidermis; intestinal bulb primordium; sensory system; and ventricular zone. Orthologous to human PACSIN3 (protein kinase C and casein kinase substrate in neurons 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:56324 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Edeling et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pacsin3 Human Ortholog

No data available

Associated With pacsin3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001060	FCH domain
Domain	IPR001452	SH3 domain
Domain	IPR031160	F-BAR domain
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	F-BAR domain	FCH domain	SH3 domain	SH3-like domain superfamily
UniProtKB:Q7ZUY8 InterPro	377
UniProtKB:A0A8M3B1H5 InterPro	516
UniProtKB:A0A8M9QGQ8 InterPro	458
UniProtKB:A0A8M2BE23 InterPro	435

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pacsin3-201 (1) Ensembl	Havana	2581 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pacsin3-202 (1) Ensembl	Havana	2629 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pacsin3-203 (1) Ensembl	Havana	307 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pacsin3-204 (1) Ensembl	Havana	283 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations