Gene
sepsecs
- ID
- ZDB-GENE-040426-859
- Name
- Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
- Symbol
- sepsecs Nomenclature History
- Previous Names
-
- sla/lpl
- zgc:55980
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have tRNA binding activity and transferase activity, transferring selenium-containing groups. Predicted to be involved in selenocysteinyl-tRNA(Sec) biosynthetic process and translation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2D. Orthologous to human SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55980 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 2D | Alliance | Pontocerebellar hypoplasia type 2D | 613811 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | O-phosphoseryl-tRNA(Sec) selenium transferase | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | SepSecS/SepCysS family |
|---|---|---|---|---|---|
|
UniProtKB:Q803A7
|
490 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sepsecs-201
(1)
|
Ensembl | 2,458 nt |
Interactions and Pathways
No data available
Plasmids
No data available