Gene

far1

ID
ZDB-GENE-040426-2908
Name
fatty acyl CoA reductase 1
Symbol
far1 Nomenclature History
Previous Names
  • fc22d12
  • mlstd2 (1)
  • wu:fc22d12
  • zgc:55416 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have fatty-acyl-CoA reductase (alcohol-forming) activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to localize to peroxisome. Is expressed in several structures, including nervous system; notochord; pronephric duct; solid lens vesicle; and ventral mesenchyme. Orthologous to human FAR1 (fatty acyl-CoA reductase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With far1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
rhizomelic chondrodysplasia punctate type 4 Alliance Peroxisomal fatty acyl-CoA reductase 1 disorder 616154
Cataracts, spastic paraparesis, and speech delay 619338
Associated With far1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013120 Fatty acyl-coenzyme A reductase-like, NAD-binding domain
Domain IPR033640 Fatty acyl-CoA reductase, C-terminal
Family IPR026055 Fatty acyl-CoA reductase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Fatty acyl-CoA reductase Fatty acyl-CoA reductase, C-terminal Fatty acyl-coenzyme A reductase-like, NAD-binding domain NAD(P)-binding domain superfamily
UniProtKB:A0A8M9PMN6 518
UniProtKB:A0A8M2BLL5 518
UniProtKB:Q803W3 432
UniProtKB:A0A8M9PYB3 400
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA far1-201 (1) Ensembl 1,972 nt
mRNA far1-202 (1) Ensembl 621 nt
mRNA far1-203 (1) Ensembl 610 nt
mRNA far1-204 (1) Ensembl 2,247 nt
mRNA far1-205 (1) Ensembl 621 nt
mRNA far1-206 (1) Ensembl 1,588 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations