Gene
xrn2
- ID
- ZDB-GENE-040426-2874
- Name
- 5'-3' exoribonuclease 2
- Symbol
- xrn2 Nomenclature History
- Previous Names
-
- wu:fb38g12
- wu:fj53d06
- zgc:55717
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have 5'-3' exoribonuclease activity and nucleic acid binding activity. Predicted to be involved in mRNA processing. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma and lung cancer. Orthologous to human XRN2 (5'-3' exoribonuclease 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55717 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 5'-3' exoribonuclease | 5'-3' exoribonuclease type 2 | Xrn1, helical domain | Xrn1, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ISJ3
|
952 | ||||
|
UniProtKB:A0A8M2B7S3
|
938 |
Interactions and Pathways
No data available
Plasmids
No data available