Gene
ppt1
- ID
- ZDB-GENE-040426-2653
- Name
- palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
- Symbol
- ppt1 Nomenclature History
- Previous Names
-
- wu:fj17f04
- zgc:63969
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation and receptor-mediated endocytosis. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63969 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neuronal ceroid lipofuscinosis 1 | Alliance | Ceroid lipofuscinosis, neuronal, 1 | 256730 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Palmitoyl protein thioesterase |
|---|---|---|---|
|
UniProtKB:F1R8J6
|
303 | ||
|
UniProtKB:Q7T3C4
|
303 |
Interactions and Pathways
No data available
Plasmids
No data available