Gene
hoga1
- ID
- ZDB-GENE-040426-2242
- Name
- 4-hydroxy-2-oxoglutarate aldolase 1
- Symbol
- hoga1 Nomenclature History
- Previous Names
-
- zgc:77082
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have 4-hydroxy-2-oxoglutarate aldolase activity. Predicted to be involved in glyoxylate catabolic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 3. Orthologous to human HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary hyperoxaluria type 3 | Alliance | Hyperoxaluria, primary, type III | 613616 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | DapA-like | Schiff base-forming aldolase, active site |
|---|---|---|---|---|
|
UniProtKB:Q6NY77
|
324 |
Interactions and Pathways
No data available
Plasmids
No data available