Gene
b2ml
- ID
- ZDB-GENE-040426-2136
- Name
- beta-2-microglobulin, like
- Symbol
- b2ml Nomenclature History
- Previous Names
-
- wu:fb66f11
- wu:fj01f08
- zgc:64161
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I and immune response. Predicted to localize to MHC class I protein complex and extracellular region. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; inflammatory bowel disease; and primary immunodeficiency disease. Is expressed in blastomere and eye. Orthologous to human B2M (beta-2-microglobulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F1G6
|
116 |
Interactions and Pathways
No data available
Plasmids
No data available