Gene

pak5

ID
ZDB-GENE-040426-2085
Name
p21 protein (Cdc42/Rac)-activated kinase 5
Symbol
pak5 Nomenclature History
Previous Names
  • pak5 (1)
  • pak6 (1)
  • pak7
  • zgc:76890
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; cytoskeleton organization; and protein phosphorylation. Is expressed in central nervous system and spinal cord. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pak5 Human Ortholog
No data available
Associated With pak5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000095 CRIB domain
Domain IPR000719 Protein kinase domain
Domain IPR028754 Serine/threonine-protein kinase PAK5, catalytic domain
Domain IPR033923 p21 activated kinase binding domain
Family IPR050285 STE20 Serine/Threonine-Protein Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036936 CRIB domain superfamily
Domain Details Per Protein
Protein Length CRIB domain CRIB domain superfamily p21 activated kinase binding domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase PAK5, catalytic domain STE20 Serine/Threonine-Protein Kinase
UniProtKB:Q6NVJ4 711
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pak7-201 (1) Ensembl 4,186 nt
mRNA pak7-202 (1) Ensembl 1,938 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations