Gene
ripk4
- ID
- ZDB-GENE-040426-2042
- Name
- receptor-interacting serine-threonine kinase 4
- Symbol
- ripk4 Nomenclature History
- Previous Names
-
- wu:fj80b10
- zgc:55705
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including EVL; digestive system; ectoderm; epidermis; and peripheral olfactory organ. Orthologous to human RIPK4 (receptor interacting serine/threonine kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55705 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| popliteal pterygium syndrome | Alliance | Popliteal pterygium syndrome, Bartsocas-Papas type 1 | 263650 |
| CHAND syndrome | 214350 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q8JHU3 | InterPro | 820 | ||||||
| UniProtKB:A0AB32U279 | InterPro | 835 | ||||||
| UniProtKB:A0AB32U3D7 | InterPro | 820 |
Interactions and Pathways
No data available
Plasmids
No data available