Gene

arhgap12b

ID

ZDB-GENE-040426-1727

Name

Rho GTPase activating protein 12b

Symbol

arhgap12b Nomenclature History

Previous Names

arhgap12
zgc:73239 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in regulation of GTPase activity. Predicted to localize to cytoplasm. Is expressed in retina and somite. Orthologous to human ARHGAP12 (Rho GTPase activating protein 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7151471 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap12b Human Ortholog

No data available

Associated With arhgap12b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001202	WW domain
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR035491	ARHGAP12, SH3 domain
Family	IPR050729	Rho GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036020	WW domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	ARHGAP12, SH3 domain	PH-like domain superfamily	Pleckstrin homology domain	Rho GTPase-activating protein	Rho GTPase-activating protein domain	Rho GTPase activation protein	SH3 domain	SH3-like domain superfamily	WW domain	WW domain superfamily
UniProtKB:A0A0R4IKK1 InterPro	841
UniProtKB:A0A8M9QME4 InterPro	882
UniProtKB:A0A8M9QIL2 InterPro	881
UniProtKB:A0A8M9QE56 InterPro	458
UniProtKB:A0A8M9Q893 InterPro	664
UniProtKB:Q6P4P5 InterPro	817
UniProtKB:A0A8M9PW53 InterPro	858

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arhgap12b-201 (1) Ensembl	Ensembl	4,227 nt	Select Tool
mRNA	arhgap12b-202 (1) Ensembl	Ensembl	831 nt	Select Tool
mRNA	arhgap12b-203 (1) Ensembl	Ensembl	463 nt	Select Tool
mRNA	arhgap12b-204 (1) Ensembl	Ensembl	4,670 nt	Select Tool ZFIN BLAST
mRNA	arhgap12b-205 (1) Ensembl	Ensembl	4,617 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations