Gene

tbl1xr1b

ID

ZDB-GENE-040426-1192

Name

TBL1X/Y related 1b

Symbol

tbl1xr1b Nomenclature History

Previous Names

tbl1xr1
zgc:63617

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have transcription corepressor activity. Predicted to be involved in histone deacetylation and regulation of transcription by RNA polymerase II. Predicted to localize to histone deacetylase complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 41. Is expressed in female organism. Orthologous to human TBL1XR1 (TBL1X receptor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6903261 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tbl1xr1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 41	Alliance	Intellectual developmental disorder, autosomal dominant 41	616944
Pierpont syndrome	Alliance	Pierpont syndrome	602342

Associated With tbl1xr1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006594	LIS1 homology motif
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR045183	F-box-like/WD repeat-containing protein Ebi-like
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat